Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is a chronic and progressive disease with a prevalence of 0.8-1% of the adult population. It is charactzerized by joint swelling, tenderness and eventual destruction.

The RA diagnostic criteria

RA diagnosis is determined by the 2010 American College of Rheumatology / European League Against Rheumatism classification criteria.
Four categories combine to form a total score of 10. A score of >= 6/10 is necessary for diagnosis.
Categories consist of: A, joint involvement, B, serolgy (RF and CCP), C, acute phase reactants (CRP and ESR), D, duration of symptoms.

RA management - early treatment is highly important

RA therapies include non steroidal anti-inflammatory drugs (NSAIDS), corticosteroids and disease modifying anti-rheumatic drugs (DMARDS) with or without biologic activity. Acting  early, with appropriate treatment has been shown to improve outcomes.

RA window of opportunity - early, effective treatment of RA is known to improve prognosis

 

 

References

Aletaha D et al. (2010)  |  Correia ML et al (2008)  |  ACR/EULAR (2010)  |  Clements JN. (2011)   

 

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.